Aclobet Ointment 10g – For External Use Only – The ACME Laboratories Ltd.

Aclobet Ointment 10g


Aclobet Ointment 10g. Aclobet Ointment 10g for external use only. clobetasol probionate BP 0.05% w/w. Aclobet Ointment 10g Each gram of ointment contains clobitasol propionate BP 0.5 mg.

Manufacturing by: The ACME Laboratories Ltd.

Indications for Aclobet ointment


Clobetasol propionate  is employed  to treat the following dermatoses in adults, the elderly  and youngsters  over one year of age.

Refractory dermatoses  lichen ruber planus  Discoid lupus erythematosus Other skin disorders that do not respond well to less potent steroids Psoriasis (except broad plaque psoriasis) Refractory dermatoses Lichen planus Discoid lupus erythematosus.

Aclobet Ointment 10g


Pharmacology of Aclobet ointment


Clobetasol propionate  may be a  highly potent topical corticosteroid. It acts as an anti-inflammatory, antipruritic and vasoconstrictive agent.

It inhibits the late phase of  allergies  by exhibiting anti-inflammatory effects through various pathways.  mastocyte  density, chemotaxis, and eosinophil activation are all reduced.

It also inhibits the metabolism of arachidonic acid and reduces  the assembly  of cytokines.


Dosage and administration of Aclobet ointment


Adults, the elderly  and youngsters  over one year of age should apply a thin layer of Clobetasol Propionate Cream or Ointment to the affected skin area twice a day and rub it in gently.

Exacerbations  are often  managed with repeated short courses of Clobetasol propionate. If necessary, the effect of Clobetasol  are often  enhanced by covering the treated area with a polyethylene sheet for more resistant lesions, especially where  there’s  hyperkeratosis.

A nocturnal occlusion  is typically  sufficient for an acceptable response. Clobetasol propionate  may be a  highly potent topical corticosteroid, so it should only be used  for 2  weeks at a time.

the utmost  weekly dose should not exceed 50 g. If possible, youth courses should be limited  to 5  days and reviewed weekly. Cutaneous  is that the  route of administration.

Creams are particularly suitable for wet or damp surfaces. Ointments are particularly useful for lesions that are dry, lichenified, or scaly.


Interactions of Aclobet ointment


Corticosteroid metabolism has been shown to be inhibited by co-administered drugs that inhibit CYP3A4 (eg, ritonavir, itraconazole),  leading to  increased systemic exposure.




It is not recommended for patients who are hypersensitive to any of the components of the product.

Rosacea,  acne , perioral dermatitis, perianal and vaginal pruritus, pruritus without inflammation, and untreated  disease of the skin  are all contraindications.


Adverse effects of Aclobet ointment


Burning and stinging sensations are  the foremost  commonly reported side effects. Itching, skin atrophy, cracking and cracking of the skin are less common side effects.

Long-term use of topical Clobetasol propionate formulations is  related to  Cushing’s syndrome in both children and adults.


Pregnancy and breastfeeding


The use of Clobetasol Propionate cream in pregnant women has produced mixed results. Corticosteroids used topically in pregnant animals can cause problems with fetal development.

The applicability of this detection to human has yet to be strong-minded.

Clobetasol propionate cream should be used during pregnancy and lactation  as long as  the expected benefit outweighs the risk. to the mother outweighs the potential risks of the treatment.


Precautions and Warnings


When using occlusive dressings, the skin should be cleansed before applying  a replacement  dressing.

In psoriasis, topical corticosteroids should be administered with caution as  they’ll  cause a rebound phenomenon and local or systemic toxicity due to reduced skin barrier function.

Treatment should be limited  to five  days if applied to the face. When using Clobetasol propionate on the eyelids,  take care  not to get it in your eyes,  because it  may cause cataracts and glaucoma.


Therapeutic class


Other corticosteroids for topical use.


Storage conditions


Keep the temperature below 30°C and protect from light and moisture. Don’t let yourself freeze.  exclude  of reach of children.

Pharmaceutical name of Aclobet ointment


ACME Laboratories Ltd


Generic Aclobet ointment


Clobetasol propionate


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